BioCarta Observe how genes interact in dynamic graphical models

Cell-Cell Interactions in Bacteria

Cell-Cell Interactions: "One current estimate suggests that more than 99% of the bacteria on earth live as cell masses (Costerton et al., 1995), a condition conducive to cell interactions. As the broader significance of multicellular microbial life has been recognized, the cell interactions that facilitate multicellularity have been revealed."

Protein Kinase Signaling Networks

Yale Scientists Decipher 'Wiring Pattern' Of Cell Signaling Networks: "Led by Michael Snyder, Lewis B Cullman Professor of Molecular, Cellular and Developmental Biology, these researchers focused on the expression and relationship between proteins of the yeast cell 'proteome,' or the proteins that are active in a cell.
Protein kinases act as regulator switches and modify their target proteins by adding a phosphate group to them. This process, called 'phosphorylation,' results in altered activity of the phosphorylated protein. It is estimated that 30% of all proteins are regulated by this process.

From the wealth of information generated by these experiments Snyder's team constructed a complex map of the regulatory networks governing the functions and activities of the kinases in the yeast cell. The map shows several distinct patterns."